团队定位和科研方向:
立足河南道地大宗的中药材资源,为河南中药材产业提质增效贡献力量。开展怀山药、怀地黄等中药材道地性的形成机制研究,基于基因组和代谢组技术深度挖掘道地药材优良种质资源性状调控基因及其活性物质的提取、分离、结构鉴定和活性评价等研究。
研究方向:怀山药道地性和品质提升研究;中药内生真菌化学与生物学研究;中药多糖结构与活性研究;中兽药和饲料添加剂研发等。
人员组成:
现有教授1名,副教授(含校聘)2名,高级实验师1人,讲师2人。博士研究生导师1人,硕士研究生导师3人;1人入选郑州市“1125”创新领军人才,1人入选河南省教育厅学术技术带头人,1人入选河南省教育厅青年骨干教师,2人入选河南农业大学青年英才。
代表性成果:
近5年主持国家自然基金联合和青年基金项目、河南省自然科学基金重点项目和青年项目、河南省科技研发联合基金、河南省科技攻关项目等国家级、省部级课题10余项。在国内外专业期刊上发表研究论文27篇。其中SCI论文11篇,最高影响因子11.5,影响因子8.0以上的文章5篇。出版专著和教材5部,授权国家发明专利2项。培养硕士研究生13人,其中1人获得河南省优秀硕士论文,2人获得河南农业大学优秀硕士论文,在读硕士研究生10人。
代表性论文:
1. Zuowei Zhao, Yanyan Qian, Yuan Ruan, et al. Physicochemical properties and biological activities of polysaccharides from the peel of Dioscorea opposita Thunb. extracted by four different methods. Food Science and Human Wellness, 2023, 12: 130-139.
2. Li Wang,Zuowei Zhao, Haoqiang Zhao, et al. Pectin polysaccharide from Flos Magnoliae (Xin Yi, Magnolia biondii Pamp. flower buds) : Hot-compressed water extraction, purification and partial structural characterization. Food Hydrocolloids, 2022, 122, 107061.
3. Yuan Ruan, Chaofei Niu, Pengzhan Zhang, et al. Acid-catalyzed water extraction of two polysaccharides from Artemisia argyi and their physicochemical properties and antioxidant activities. Gels, 2022, 8: 5.
4. Li Wang, Yi-gui Mao, Xiang Zeng, et al. Structure and bioactivities of a novel polysaccharide extracted from Dendrobium huoshanense by subcritical water. Frontiers in Nutrition, 2022, 9: e977871.
5. Yanyan Qian, Li Wang, Zhiqiang Zhang, et al. Physical-chemical properties of heteropolysaccharides from different processed forms of Rehmanniae radix. Process Biochemistry, 2022, 121: 481-492.
6. Xinxin Li, Zhiqiang Zhang, Li Wang, et al. Three-phase extraction of polysaccharide from Stropharia rugosoannulata: Process optimization, structural characterization and bioactivities. Frontiers in Immunology, 2022, e994706.
7. Pengzhan Zhang, Li Wang, Yanyan Qian, et al. Influences of extraction methods on physicochemical and functional characteristics of three new bulbil starches from Dioscorea opposita Thunb. cv. Tiegun. Molecules, 2019, 24(6): 2232.
8. Li Wang, Peng-zhan Zhang, Jin-wen Shen, et al. Physicochemical properties and bioactivities of original and Se-enriched polysaccharides with different molecular weights extracted from Pleurotus ostreatus. International Journal of Biological Macromolecules, 2019, 141, 150-160.
9. Li Wang, Huamin Liu, Chunyan Zhu, et al. Chinese quince seed gum: Flow behaviour, thixotropy and viscoelasticity. Carbohydrate Polymers. 2019, 209: 230-238.
10. Yi Liu, Chao-Fei Niu, Yi Wang, et al. Preparation, structural characteristics and antioxidant activity of polysaccharide and its metal chelates from the peel of Dioscorea oppositifolia L. Natural Product Research, 2023, DOI: 10.1080/14786419.2023.2255917.