苟明月,博士,教授,博士生导师,河南省特聘教授。现任农学院作物基因组与分子育种中心主任、国家玉米改良(郑州)分中心副主任。
主要开展玉米抗病(逆)机制、细胞壁形成机制及分子育种研究工作。发现CPR30/CPR1、SIZ1、BON1-HSC70等基因或蛋白复合体参与植物抗病防御反应调控的新机制;发现MSBPs、CB5D、KFBs、MYB107等参与植物细胞壁合成调控的新基因,并阐明了这些基因介导的木质素和木栓质合成酶代谢区室复合体形成、电子传递、泛素化修饰与降解、转录调控等机制;在玉米广谱抗病性及南方锈病抗性研究中取得重要进展。
在Nature Plants、Plant Cell、Plant Physiology、Plant Journal、The Crop Journal等期刊以第一作者或通讯作者身份发表论文14篇,在Nature Communications、 Nature Genetics等期刊合作发表论文10篇,获国家发明专利1项;研究成果被Science Daily等媒体报道,论文被引用1400余次(谷歌学术);担任Plant Cell、Plant Physiology、Journal of Experimental Botany等10余个植物学期刊审稿人;2018年至今先后获得河南省特聘教授、“中原千人计划”青年拔尖人才、河南省高层次人才、河南省杰出青年科学基金获得者等荣誉。
联系方式:0371-56990319;
mingyuegou@henau.edu.cn;
mingyuegou@163.com;
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龙子湖校区第一实验楼南405(办公室)、南403(实验室)。
Web: https://www.researchgate.net/profile/Mingyue-Gou
https://scholar.google.com/citations?user=0jFPU1IAAAAJ&hl=en(谷歌学术)
研究方向:
1、 玉米抗病(逆)机制解析与分子育种;
2、 植物细胞壁与抗病(逆)性交叉研究;
3、 植物生长与抗病平衡机理研究。
讲授课程:植物生物技术、分子生物学、农业微生物学、作物抗病与抗逆生物学。
教育与研究/工作经历:
2017年-至今 河南农业大学教授;
2012-2018年 美国布鲁克海文国家实验室生物系,副研究员;
2009-2012年 美国康奈尔大学植物系,博士后;
2003-2009年 中国农业大学生物学院,理学博士学位;
1999-2003年 西南农业大学(现西南大学)农学院,农学学士学位。
研究项目:
1、国家自然科学基金(联合基金重点项目):黄淮地区玉米叶部病害广谱抗病基因克隆与广谱抗性机制解析,2021-2024,主持人;
2、河南省杰出青年基金项目:BLES10 调控玉米广谱抗病性机制解析及其育种应用, 2021-2023,主持人;
3、中原千人计划-青年拔尖人才项目:作物抗病与细胞壁合成机制研究,2020-2022,主持人;
4、美国能源部(DOE)专项,Metabolic plasticity, macromolecular organization, and post-translational regulation of lignin biosynthesis 2012 -2020,参加;
5、美国国家自然科学基金(NSF)项目, Molecular mechanisms underlying temperature modulation of defense responses, 2009 -2013,参加;
6、美国国家自然科学基金(NSF)项目, Regulation of a resistance gene by BON1 in Arabidopsis,2007 -2010,参加。
研究论文/发明专利:
1.
Xiaohuan Mu#, Zhuangzhuang Dai#, Zhanyong Guo,
Hui Zhang,
Jianping Yang,
Xinke Gan,
Jiankun Li,
Zonghua Liu,
Jihua Tang*,
Mingyue Gou* (
2021). Systematic dissection of disease resistance to southern corn rust by bulked-segregant and transcriptome analysis.
The Crop Journal, DOI:
10.1016/j.cj.2021.07.001
2.Xiaohuan Mu
#, Jiankun Li
#, Liping Xu, Zhuangzhuang Dai, Tianyuan Fan, Teng Jing, Mengyao Chen, and
Mingyue Gou* (
2021). Commonly and specifically activated defense responses in maize disease lesion mimics mutants revealed by integrated transcriptomics and metabolomics analysis.
Frontiers in Plant Science, 12:1-19
3. Guangwei Li, Lijian Wang,Jianping Yang*,Hang He, Huaibing Jin, Xuming Li, Tianheng Ren, Zhengnong Ren, Feng Li, Xue Han, Xiaoge Zhao, Lingli Dong, Yiwen Li, Zhongping Song, Zehong Yan, Nannan Zheng, Cuilan Shi, Zhaohui Wang, Shuling Yang, Zijun Xiong, Menglan Zhang, Guanghua Sun, Xu Zheng,
Mingyue Gou, Changmian Ji, Junkai Du, Hongkun Zheng, Jaroslav Doleze, Xing Wang Deng, Nils Stein, Qinghua Yang*, Kunpu Zhang*, Daowen Wang* (
2021). A high-quality genome assembly highlights rye genomic characteristics and agronomically important genes.
Nature Genetics, 53(4):574-584
4.
Mingyue Gou#, Xiaoman Yang
#, Yunjun Zhao
#, Xiuzhi Ran, Yanzhai Song, and Chang-Jun Liu* (
2019). Cytochrome b5 is an obligate electron shuttle protein for syringyl lignin biosynthesis in Arabidopsis.
Plant Cell, 31:1344-1366.
5.
Mingyue Gou, Xiuzhi Ran, Dwight W. Martin and Chang-Jun Liu*
(2018). The scaffold proteins of lignin biosynthetic cytochrome P450 enzymes
. Nature Plants, 4: 299-310.
6. Dong-Lei Yang, Zhenying Shi, Yongmei Bao, Jiapei Yan, Ziyuan Yang, Huiyun Yu, Yun Li,
Mingyue Gou, Shu Wang, Baohong Zou, Dachao Xu, Zhiqi Ma, Jitae Kim, Jian Hua*
(2017). Calcium pumps and interacting BON1 protein modulate calcium signature, stomatal closure, and plant immunity.
Plant Physiology, 175(1):424-437.
7.
Mingyue Gou#, Quansheng Huang
#, Weiqiang Qian, Zemin Zhang, Zhenhua Jia, and Jian Hua* (
2017). Sumoylation E3 Ligase SIZ1 modulates plant immunity partly through the immune receptor gene
SNC1 in Arabidopsis.
Molecular Plant-Microbe Interactions, 30(4):334-342.
8.
Mingyue Gou, Guichuan Hou, Huijun Yang, Xuebin Zhang, Yuanheng Cai, Guoyin Kai, and Chang-Jun Liu*
(2017).The MYB107 transcription factor positively regulates suberin biosynthesis.
Plant Physiology, 173 (2):1045-1058.
9.
Mingyue Gou#, Zemin Zhang
#, Ning Zhang
#, Quansheng Huang, Jacqueline Monaghan, Huijun Yang, Zhenying Shi, Cyril Zipfel, and Jian Hua*
(2015). Opposing effects on two phases of defense responses from concerted actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis.
Plant Physiology, 169(3):2304-2323.
10. Xuebin Zhang,
Mingyue Gou, Chunrong Guo, Huijun Yang, Chang-Jun Liu*
(2014). Down-regulation of the kelch domain-containing F-box protein in Arabidopsis enhances the production of (poly)phenols and tolerance to UV-radiation.
Plant Physiology, 167(2):337-50
11. Chang-Jun Liu*, Yuanheng Cai, Xuebin Zhang,
Mingyue Gou, Huijun Yang
(2014). Tailoring lignin biosynthesis for efficient and sustainable biofuel production.
Plant Biotechnology Journal, 12(9):1154-62.
12. Xiaoqing Wang,
Mingyue Gou, Huahu Bu, Shengxue Zhang, Guoying Wang*
(2014).Proteomic analysis of
Arabidopsis constitutive expresser of pathogenesis-related gene1 (
Cpr30/cpr1-2) mutant.
Plant omics journal, 7(3):123-132
13. Kewei Zhang, Ondrej Novak, Zhaoyang Wei,
Mingyue Gou, Xuebin Zhang, Yong Yu, Huijun Yang, Yuanheng Cai, Miroslav Strnad, and Chang-Jun Liu*
(2014). Arabidopsis ABCG14 protein controls the acropetal translocation of root-synthesized cytokinins.
Nature Communications | 5:3274 | DOI: 10.1038/ncomms4274.
14. Xuebin Zhang
#,
Mingyue Gou#, Chang-Jun Liu*
(2013). Kelch repeat F-box proteins regulate phenylpropanoid biosynthesis via controlling the turnover of Phenylalanine Ammonia-Lyase.
Plant Cell, 25: 4994–5010.
15.
Mingyue Gou and Jian Hua*
(2012). Complex regulation of an
R gene
SNC1 revealed by auto-immune mutants.
Plant Signaling & Behavior, 7(2): 213–216.
16.
Mingyue Gou, Zhenying Shi, Ying Zhu, Zhilong Bao, Guoying Wang and Jian Hua*
(2012). The F-box protein CPR1/CPR30 negatively regulates R protein SNC1 accumulation.
Plant Journal, 69: 411–420.
(Recommended as top article from F1000's faculty of leading experts)
17. Yongqing Li
#,
Mingyue Gou#, Qi Sun, and Jian Hua*
(2010). Requirement of calcium binding, myristoylation, and protein-protein interaction for the copine BON1 function in Arabidopsis.
Journal of Biological Chemistry, 285(39):29884-91.
18. Jun Zheng
#, Junjie Fu
#,
Mingyue Gou#, Junling Huai, Yunjun Liu, Min Jian; Quansheng Huang, Xiying Guo, Zhigang Dong, Hongzhi Wang, Guoying Wang*
(2010). Genome-wide transcriptome analysis of two maize inbred lines under drought stress.
Plant Molecular Biology, 72(4-5):407-21.
19.
Mingyue Gou#, Nan Su
#, Jun Zheng, Junling Huai, Guangheng Wu, Jinfeng Zhao, Junguang He, Dingzhong Tang, Shuhua Yang, and Guoying Wang*
(2009). An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.
Plant Journal, 60(5):757-70.
20. Jinfeng Zhao, Zhenfei Sun, Jun Zheng, Xiying Guo, Zhigang Dong, Junling Huai,
Mingyue Gou, Junguang He, Yongsheng Jin, Jianhua Wang, Guoying Wang*
(2009). Cloning and characterization of a novel CBL-interacting protein kinase from maize.
Plant Molecular Biology, 2009, 69:661–674.
21. Jun Zheng, Jinfeng Zhao, Jinpeng Zhang, Junjie Fu,
Mingyue Gou, Zhigang Dong, Wei Hou, Jinping Jia, Quansheng Huang and Guoying Wang*
(2006). Comparative expression profiles of maize genes under high-salinity, cold and abscisic acid application using a water stress specific cDNA macroarray.
Plant Science, 170:1125-1132.
22. 程相杰、徐莉萍、母小焕、
苟明月*
(2022), 玉米天冬氨酸蛋白酶基因家族的鉴定与表达分析。玉米科学 30 (1):53-62。
23. 白云凤、赵晋锋、郑军、张锦鹏、王茅雁、苟明月、董志刚、 杨红春、王国英*
(2006),反义外壳蛋白基因介导的抗SCMV转基因玉米研究。 作物学报 32(5):661-665。
24. 白云凤、王国英*、苟明月、董志刚、赵晋锋
(2006), 农杆菌介导玉米转基因的影响因素研究。中国生态农业学报 14(3):173-175。
25. 苟明月*、荆腾、武玉莹、范田源、李见坤
(2022), 控制玉米株高的基因、其编码的蛋白质以及应用,CN202011490418.7
(国家发明专利)。
注:*通讯作者、
#并列第一作者